Naringin (naringenin) related research is mainly focused on its biological activity, pharmacological effects and potential applications, the following is a detailed summary of its related research:
1. Biological activities and pharmacological effects
Antioxidant effects:
Naringin has significant antioxidant effects, which can scavenge free radicals in the body and reduce oxidative stress, thus protecting cells from damage. Its high antioxidant activity helps to prevent chronic diseases.
Anti-inflammatory effects:
Naringin can inhibit the inflammatory response and reduce tissue damage caused by inflammation. Its mechanism of action includes the inhibition of the production and release of pro-inflammatory factors, and it is suitable for the treatment of a variety of inflammatory diseases, such as arthritis, asthma and dermatitis.
Improves blood lipids:
Naringenin helps to lower the level of low-density lipoprotein cholesterol (LDL-C) while boosting the level of high-density lipoprotein cholesterol (HDL-C), which improves the lipid profile and prevents cardiovascular diseases.
Anti-cancer potential:
Some studies have found that naringenin may have the effect of inhibiting cancer cell proliferation and inducing apoptosis in cancer cells, which may have a preventive effect on certain types of cancer such as breast cancer and colon cancer.
Other pharmacological effects:
Naringin also has a variety of pharmacological effects such as anti-osteoporosis, anti-viral, anti-mutagenic, anti-allergic, anti-ulcer, analgesic, and hypotensive. It also lowers blood cholesterol, reduces thrombus formation, and improves local microcirculation and nutrient supply.
2. Potential Applications
Pharmaceutical field:
Naringin can be used to produce drugs against cardiovascular and cerebrovascular diseases, inflammatory diseases, cancer and other diseases. Its anti-inflammatory, antioxidant and lipid improvement effects provide new ideas for the treatment of these diseases.
Nutraceutical field:
Naringin can be used as an ingredient in nutraceuticals to enhance immunity, promote metabolism, and protect cardiovascular health. Its natural and safe characteristics make it a broad application prospect in the field of health products.
3. Food and beverage field:
Naringin can be used as food and beverage additives, mainly in functional beverages such as gummies, beer and refreshing beverages to improve taste and increase nutritional value.
Chemical synthesis field:
Naringin is also widely used in chemical synthesis as an important raw material. For example, under alkaline conditions, the pyranone ring opens and is hydrogenated to prepare dihydrochalcone sweetener.