Nobiletin is a polymethoxyflavonoid found in citrus fruits and is one of the main components of tangerine peel. Below is a detailed description of Nobiletin : A…:
1.Basic Information
Chinese name: Nobiletin
English Name: Nobiletin
Chemical formula: C21H22O8
Molecular weight: 402.39
CAS No.: 478-01-3
Physical state: colorless crystal or white to light yellow crystalline powder
Melting point: 137-138°C
Water solubility: slightly soluble in water and ether
2.Plant Source
Nobiletin is mainly derived from the pericarp of plants in the family of Rutaceae, such as the pericarp of Kawasaki orange (Citrus nobilis Loura.), sour orange (C. aurantium L.), and the leaves and stems of mandarin orange (C. reticulata Blanco).
3.Production process
The production process of Nobiletin mainly includes alcohol extraction, extraction, chromatography, crystallization and other processes.
4.Pharmacological effects
Nobiletin has a variety of pharmacological effects, including but not limited to:
Anti-coagulation and anti-thrombosis: helps maintain healthy blood circulation.
Anti-cancer: It has inhibitory effects on a variety of cancer cells.
Antifungal: it is effective against fungal infections.
Anti-inflammatory: able to reduce inflammatory reactions.
Anti-allergic: it has a certain relief effect on allergic reactions.
Anticholinesterase and antiepileptic: with neuroprotective effects.
Regulate lipid metabolism: can improve obesity, fatty liver, diabetes and atherosclerosis and other lipid metabolism disorders related diseases.
Lowering blood lipids: Studies by a Canadian research team have shown that Nobiletin can prevent postprandial hyperlipidemia by attenuating the adverse effects of a high-fat diet through a variety of pathways.
Delay aging: Delay aging of skeletal muscle by improving mitochondrial function.
5.Fields of application
Nobiletin has a wide range of applications in the fields of medicine, health products and cosmetics due to its multiple pharmacological effects. For example, it can be added into related products as antioxidant, anti-inflammatory agent, anti-cancer agent, etc. to enhance the efficacy and added value of the products.
6.Cautions
Despite Nobiletin’s various pharmacological effects, its safety and efficacy should be noted in practical application. It is recommended to use it under the guidance of professional doctors and follow the relevant instructions and precautions for use.
In conclusion, Nobiletin is a natural product with multiple pharmacological effects and has a wide range of application prospects. With the deepening of scientific research, it is believed that people’s understanding of Nobiletin will be more comprehensive and in-depth.