Naringin is a flavonoid compound mainly found in the rind and pulp of grapefruit (e.g. grapefruit, tangerine, orange) of the Brassicaceae family, which has a wide range of pharmacological activities and application value.<\/p>\n\n\n\n
1. Chemical Properties<\/p>\n\n\n\n
Molecular formula: C\u2082\u2087H\u2083\u2082O\u2081\u2084<\/p>\n\n\n\n
Molecular weight: 580.54 g\/mol<\/p>\n\n\n\n
Physical and Chemical Properties: White needle-like crystals, extremely bitter taste, melting point is about 83\u2103 (six to eight hydrate), after drying the melting point rises to 171\u2103 (dihydrate). Soluble in methanol, ethanol, acetone, hot water, slightly soluble in cold water, insoluble in petroleum ether, ether and other non-polar solvents.<\/p>\n\n\n\n
2. Pharmacological effects<\/p>\n\n\n\n
Antioxidant: Scavenging free radicals, inhibiting melanin production, with whitening effect.<\/p>\n\n\n\n
Anti-inflammatory: inhibit the release of inflammatory mediators, suitable for arthritis, asthma, dermatitis and other inflammatory diseases.<\/p>\n\n\n\n
Cardiovascular protection:<\/p>\n\n\n\n
Increase coronary blood flow, improve myocardial ischemia.<\/p>\n\n\n\n
Lowering blood pressure, reducing thrombosis, regulating blood lipids (lowering cholesterol and triglycerides).<\/p>\n\n\n\n
Antibacterial and antiviral: Inhibit bacteria such as Staphylococcus aureus and Escherichia coli, inhibit yeast and fungi, and have preventive effect on viral infections.<\/p>\n\n\n\n
Hypoglycemic: naringenin in fresh grapefruit juice has insulin-like effects and can lower blood sugar.<\/p>\n\n\n\n
Others: antispasmodic, enhance the role of vitamin C, expectorant and cough.<\/p>\n\n\n\n
3. The extraction method<\/p>\n\n\n\n
Solvent extraction method: the use of naringin in methanol or ethanol solubility, extraction by leaching, filtration, concentration, purification and other steps.<\/p>\n\n\n\n
Alkaline acid precipitation method: open-loop dissolution under alkaline conditions, closed-loop precipitation under acidic conditions.<\/p>\n\n\n\n
Microwave\/Ultrasonic Assisted Extraction: Combined with traditional solvent method to improve extraction efficiency.<\/p>\n\n\n\n
Supercritical fluid extraction: Utilizing the dissolving ability of supercritical carbon dioxide to achieve efficient separation.<\/p>\n\n\n\n
IV. Application Fields<\/p>\n\n\n\n
Medicine: used in the treatment of cardiovascular and cerebrovascular diseases, diabetes, inflammatory diseases, etc.<\/p>\n\n\n\n
Food: as natural antioxidant, sweetener (e.g. neohesperidin dihydrochalcone) and coloring.<\/p>\n\n\n\n
Cosmetics: Used in whitening and anti-aging products.<\/p>\n\n\n\n
Health care products: developed as dietary supplements to assist in regulating blood lipids and blood pressure.<\/p>\n","protected":false},"excerpt":{"rendered":"
Naringin is a flavonoid compound mainly found in the ri […]<\/p>\n","protected":false},"author":3,"featured_media":1877,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1876","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/naringine.com\/index.php?rest_route=\/wp\/v2\/posts\/1876","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/naringine.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/naringine.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/naringine.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/naringine.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1876"}],"version-history":[{"count":1,"href":"https:\/\/naringine.com\/index.php?rest_route=\/wp\/v2\/posts\/1876\/revisions"}],"predecessor-version":[{"id":1878,"href":"https:\/\/naringine.com\/index.php?rest_route=\/wp\/v2\/posts\/1876\/revisions\/1878"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/naringine.com\/index.php?rest_route=\/wp\/v2\/media\/1877"}],"wp:attachment":[{"href":"https:\/\/naringine.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1876"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/naringine.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1876"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/naringine.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1876"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}