Overview<\/p>\n\n\n\n
Ginkgo (Ginkgo biloba) is a large tree with fan-shaped leaves. The leaves are commonly included in supplements and taken by mouth for memory problems.<\/p>\n\n\n\n
The ginkgo tree is thought to be one of the oldest living trees, dating back more than 200 million years. It is native to China, Japan, and Korea, but is also now grown in Europe and the United States. It seems to improve blood circulation, and might also act as an antioxidant to slow down changes in the brain.<\/p>\n\n\n\n
Because ginkgo has been around for so long, people have used it for many purposes. It’s commonly taken by mouth for memory and thought problems, anxiety, vision problems, and many other conditions, but there is no good scientific evidence to support most of these uses.<\/p>\n\n\n\n
Uses & Effectiveness<\/p>\n\n\n\n
Possibly Effective for<\/p>\n\n\n\n
Anxiety. Taking a specific ginkgo extract called EGb 761 (Dr. Willmar Schwabe Pharmaceuticals) by mouth for 4 weeks can reduce symptoms of anxiety by a small amount.<\/p>\n\n\n\n
Diseases, such as Alzheimer disease, that interfere with thinking (dementia). Taking ginkgo 240 mg by mouth daily may slightly improve dementia symptoms. Ginkgo doesn’t seem to prevent dementia from developing or getting worse.<\/p>\n\n\n\n
Hearing loss. In patients with sudden hearing loss, giving ginkgo by IV along with regular treatments can help to improve hearing. It’s not clear if oral ginkgo is helpful. IV products can only be given by a healthcare provider.<\/p>\n\n\n\n
Premenstrual syndrome (PMS). Taking ginkgo leaf extract by mouth seems to relieve breast tenderness and other symptoms associated with PMS. For this use, it is started during the 16th day of the menstrual cycle and continued until the 5th day of the following cycle.<\/p>\n\n\n\n
Schizophrenia. Taking ginkgo leaf extract by mouth daily in addition to conventional antipsychotic medications for 8-16 weeks can reduce some symptoms of schizophrenia. It might also reduce side effects from antipsychotic medications, like thirst, constipation, and tardive dyskinesia, a movement disorder.<\/p>\n\n\n\n
Stroke. Taking ginkgo extract by mouth or by IV along with standard therapy seems to improve thinking, memory, and the ability to complete activities of daily living in people who are recovering from a stroke. Taking ginkgo extract by mouth might not be as effective as IV. But IV products can only be given by a healthcare provider.<\/p>\n\n\n\n
A movement disorder often caused by antipsychotic drugs (tardive dyskinesia). Taking ginkgo by mouth seems to reduce the severity of movement disorders in patients taking antipsychotic drugs.<\/p>\n\n\n\n
Dementia caused by reduced blood flow to the brain (vascular dementia). Taking ginkgo extract by mouth seems to improve memory and thinking skills in patients with this condition.<\/p>\n\n\n\n
Dizziness (vertigo). Taking ginkgo leaf extract by mouth seems to improve symptoms of dizziness caused by balance disorders. It isn’t clear if helps to improve symptoms of vertigo in people with a condition that causes decreased blood flow to the brain.<\/p>\n\n\n\n
Possibly Ineffective for<\/p>\n\n\n\n
Decline in memory and thinking skills that occurs normally with age. Taking ginkgo by mouth doesn’t improve memory and thinking skills in elderly people.<\/p>\n\n\n\n
Sexual problems caused by antidepressants (antidepressant-induced sexual dysfunction). Taking ginkgo leaf extract by mouth doesn’t improve sexual problems caused by antidepressant drugs.<\/p>\n\n\n\n
Heart disease. Taking ginkgo by mouth doesn’t reduce the chance of having a heart attack, chest pain, or stroke in elderly people.<\/p>\n\n\n\n
Decline in memory and thinking skills in people treated with cancer drugs. Taking ginkgo by mouth does not prevent thinking problems caused by chemotherapy in people being treated for breast cancer.<\/p>\n\n\n\n
High blood pressure. Taking ginkgo leaf extract by mouth for up to 6 years does not reduce blood pressure in older people with high blood pressure.<\/p>\n\n\n\n
Multiple sclerosis (MS). Taking ginkgo leaf extract or ginkgolide B, a specific chemical found in ginkgo extract, by mouth doesn’t improve mental function or disability in people with multiple sclerosis.<\/p>\n\n\n\n
Ringing in the ears (tinnitus). Taking ginkgo leaf extract by mouth does not seem to improve ringing in the ears.<\/p>\n\n\n\n
There is interest in using ginkgo for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.<\/p>\n\n\n\n
Side Effects<\/p>\n\n\n\n
When taken by mouth: Ginkgo LEAF EXTRACT is likely safe for most people. It can cause some minor side effects such as stomach upset, headache, dizziness, and allergic skin reactions. There is also some concern that ginkgo leaf extract might increase the risk of bruising and bleeding or cause arrhythmia.<\/p>\n\n\n\n
The ROASTED SEED or CRUDE GINKGO PLANT are possibly unsafe when taken by mouth. Eating more than 10 roasted seeds daily can cause serious side effects such as seizures. Eating FRESH SEEDS may lead to death. They are poisonous and considered dangerous.<\/p>\n\n\n\n
When applied to the skin: There isn’t enough reliable information to know if ginkgo is safe.<\/p>\n\n\n\n
Special Precautions and Warnings<\/p>\n\n\n\n
When taken by mouth: Ginkgo LEAF EXTRACT is likely safe for most people. It can cause some minor side effects such as stomach upset, headache, dizziness, and allergic skin reactions. There is also some concern that ginkgo leaf extract might increase the risk of bruising and bleeding or cause arrhythmia.<\/p>\n\n\n\n
The ROASTED SEED or CRUDE GINKGO PLANT are possibly unsafe when taken by mouth. Eating more than 10 roasted seeds daily can cause serious side effects such as seizures. Eating FRESH SEEDS may lead to death. They are poisonous and considered dangerous.<\/p>\n\n\n\n
When applied to the skin: There isn’t enough reliable information to know if ginkgo is safe.<\/p>\n\n\n\n
Pregnancy: Ginkgo is possibly unsafe when taken by mouth during pregnancy. It might cause early labor or extra bleeding during delivery if used near that time.Breast-feeding: There isn’t enough reliable information to know if ginkgo is safe to use when breast-feeding. Stay on the safe side and avoid use.<\/p>\n\n\n\n
Children: Ginkgo leaf extract is possibly safe when taken by mouth for a short time. A specific combination of ginkgo leaf extract plus American ginseng might be safe in children when used short-term. Do not let children eat the ginkgo seed. The fresh seeds have caused seizures and death in children.<\/p>\n\n\n\n
Bleeding disorders: Ginkgo might make bleeding disorders worse. If you have a bleeding disorder, don’t use ginkgo.<\/p>\n\n\n\n
Cross-reactivity: People who are allergic to poison ivy, poison oak, poison sumac, mango rind, or cashew shell oil might also be allergic to ginkgo.<\/p>\n\n\n\n
Diabetes: Ginkgo might interfere with the management of diabetes. If you have diabetes, monitor your blood sugar closely.<\/p>\n\n\n\n
Seizures: Ginkgo might cause seizures. If you have ever had a seizure, don’t use ginkgo.<\/p>\n\n\n\n
Deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD): Ginkgo might cause severe anemia in people who have G6PD enzyme deficiency. Until more is known, use cautiously or avoid using ginkgo if you have G6PD deficiency.<\/p>\n\n\n\n
Infertility: Ginkgo use might interfere with getting pregnant. Discuss the use of ginkgo with your healthcare provider if you are trying to get pregnant.<\/p>\n\n\n\n
Surgery: Ginkgo might slow blood clotting. It might cause extra bleeding during and after surgery. Stop using ginkgo at least 2 weeks before a scheduled surgery.<\/p>\n\n\n\n
Interactions<\/p>\n\n\n\n
Major Interaction<\/p>\n\n\n\n
Do not take this combination<\/p>\n\n\n\n
Efavirenz (Sustiva) interacts with GINKGO<\/p>\n\n\n\n
Efavirenz is used to treat HIV infection. Taking ginkgo extract along with efavirenz might decrease the effects of efavirenz. Before taking ginkgo, talk to your healthcare provider if you take efavirenz.<\/p>\n\n\n\n
Talinolol interacts with GINKGO<\/p>\n\n\n\n
Taking ginkgo leaf extract multiple times per day might increase levels of talinolol. This might increase the effects and side effects of talinolol. But taking a single dose of ginkgo does not seem to affect talinolol levels.<\/p>\n\n\n\n
Be cautious with this combination<\/p>\n\n\n\n
Alprazolam (Xanax) interacts with GINKGO<\/p>\n\n\n\n
Taking ginkgo along with alprazolam might decrease the effects of alprazolam in some people.<\/p>\n\n\n\n
Ibuprofen (Advil, others) interacts with GINKGO<\/p>\n\n\n\n
Ginkgo might slow blood clotting. Ibuprofen can also slow blood clotting. Taking ginkgo with ibuprofen might slow blood clotting too much and increase the chance of bruising and bleeding. Before taking ginkgo, talk to your healthcare provider if you are taking ibuprofen.<\/p>\n\n\n\n
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with GINKGO<\/p>\n\n\n\n
Some medications are changed and broken down by the liver. Ginkgo might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.<\/p>\n\n\n\n
Dosing<\/p>\n\n\n\n
Ginkgo has most often been used by adults in doses of 60-240 mg by mouth daily for up to 6 months. Dosing might vary depending on the specific formulation used. Products that have been studied the most are often standardized to contain ginkgo leaf extracts. Speak with a healthcare provider to find out what dose might be best for a specific condition.<\/p>\n\n\n\n
Keep in mind that quality issues are common with ginkgo products. Lower quality manufacturers might use cheaper ingredients, like rutin and quercetin, instead of ginkgo. These chemicals both occur naturally in ginkgo, so adding them to ginkgo products can make the products look like ginkgo on some tests. But these products would not have the same effects as ginkgo.<\/p>\n","protected":false},"excerpt":{"rendered":"
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